The Only Medical Therapy Proven
to Shrink Tumors in Acromegaly
Sandostatin® LAR Depot (octreotide acetate for injectable suspension), the number one prescribed somatostatin analogue in the world, is the only medical therapy clinically proven to reduce tumor size in patients with acromegaly.
Help Take Control With Tumor Reduction
In two separate studies, in patients who had not been previously treated for acromegaly, Sandostatin® LAR Depot provided a 36% median reduction in tumor volume after 48 weeks—and more than 20% of this tumor shrinkage was reported after just 24 weeks of therapy. One notable finding was that none of the study participants experienced an increase in tumor size while on treatment with Sandostatin® LAR Depot.
Well-Tolerated Over the Long Term
Sandostatin® LAR Depot is also proven to be well-tolerated over the long term. And Sandostatin® LAR Depot has been used to treat acromegaly for nearly a decade, so you can feel confident that you're getting well-tolerated treatment with a proven track record.1,3
Sandostatin® LAR Depot (octreotide acetate for injectable suspension) is indicated for long-term maintenance therapy in acromegalic patients who have had an inadequate response to surgery and/or radiotherapy, or for whom surgery and/or radiotherapy is not an option. The goal of treatment in acromegaly is to reduce GH and IGF-1 levels to normal.
Important Safety Information:
As with immediate release Sandostatin® Injection, the most frequently reported drug-related adverse events were biliary disorders (52%), gastrointestinal disorders (7% to 36%), and injection-site pain (2% to 11%). Hypoglycemia (2%), hyperglycemia (15%), and hypothyroidism (2%) have been reported. While not measured in acromegalic patients receiving Sandostatin® LAR Depot, ECG changes have been reported in patients receiving immediate release Sandostatin® Injection; the degree to which these abnormalities are related to octreotide acetate is not clear, as many acromegalics have cardiovascular disease. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
